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Gritsun, T. and Stegenga, J. and le Feber, J. and Rutten, W.L.C.
(2009)
Network bursts in cortical neuronal cultures: 'noise - versus pacemaker'- driven neural network simulations.
In: Proceedings of the 4th Int. IEEE EMBS Conf. on Neural Engineering, 29 april - 2 may 2009, Antalya, Turkey.
pp. 626-628.
IEEE Engineering in Medicine and Biology Society.
ISBN 978-1-4244-2073-5
Full text available as:
Official URL: http://dx.doi.org/10.1109/NER.2009.5109374  AbstractIn this paper we address the issue of spontaneous bursting activity in cortical neuronal cultures and explain what might cause this collective behavior using computer simulations of two different neural network models. While the common approach to acivate a passive network is done by introducing synaptic noise, we show that a small subset of pacemaker neurons can trigger network bursts which better resemble experimental bursts.
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